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Patient instructions

Diazepam Vaginal Suppository Patient Instructions

These instructions are for diazepam suppositories prepared by the pharmacy for vaginal use. Diazepam is a targeted controlled substance. Available by prescription only; refill rules apply.

Sedation precautions

Diazepam can cause drowsiness, dizziness, slowed reaction time, and impaired coordination. Avoid driving or risky tasks until you know how it affects you.

Avoid combining sedatives

Alcohol, cannabis, opioids, sleep medicines, and some other medicines can increase sedation and breathing risk.

Timing matters

Many directions use bedtime dosing, but follow your prescription label. Ask before changing the schedule.

Before Use

  1. 1Read the prescription label and confirm the dose, route, timing, and storage directions.
  2. 2Use only for the person named on the prescription.
  3. 3Review alcohol, cannabis, sleep medicines, opioid pain medicines, seizure medicines, and other sedating medicines with the prescriber or pharmacist.
  4. 4Plan the dose for a time when drowsiness or impaired coordination can be managed safely.

Insertion Steps

  1. 1Wash your hands before handling the suppository.
  2. 2If the suppository feels soft, leave it wrapped and chill it briefly before opening.
  3. 3Remove one suppository from the package.
  4. 4Lie down or use the position recommended by your care team.
  5. 5Insert the suppository gently into the vagina as directed on the label.
  6. 6Remain lying down for a few minutes if that helps reduce leakage.
  7. 7Wash your hands after insertion.

Storage, Missed Doses, and Refills

Follow the storage instructions on the label. Keep suppositories away from heat, children, pets, and anyone not named on the prescription.

If you miss a dose, do not double up unless the prescriber gives that direction. Ask if you are unsure what to do.

Refill timing may be limited by controlled substance rules and the prescriber's directions. Plan ahead if ongoing treatment is prescribed.

When to Call or Seek Help

  • Extreme sleepiness, confusion, fainting, slowed breathing, or trouble waking occurs.
  • Dizziness, poor coordination, or drowsiness makes normal activities unsafe.
  • Pain is worsening, new pelvic symptoms appear, or irritation becomes significant.
  • Pregnancy is possible, pregnancy status changes, or breastfeeding questions come up.
  • The prescription label, route, timing, or refill rules are unclear.