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Patient instructions

Progesterone Vaginal Suppository Instructions

These instructions are for progesterone suppositories prepared by the pharmacy for vaginal use. Your prescription label and prescriber directions should guide use.

Leakage can happen

Some melted base may leak after insertion. A liner can help protect clothing.

Timing can matter

If your directions are tied to cycle dates, procedures, lab work, or pregnancy care, confirm timing with your prescriber.

Storage varies

Follow the storage instructions on your label. Some suppositories need refrigeration; others may be stored differently.

Before Use

  1. 1Read the prescription label and confirm the dose, route, and schedule.
  2. 2Wash your hands before handling the suppository.
  3. 3Use the product at the time of day written on your prescription label.
  4. 4Ask the prescriber before changing timing if this is part of fertility treatment, cycle timing, or pregnancy care.

Insertion Steps

  1. 1Remove one suppository from the package.
  2. 2If the suppository feels soft, leave it in its wrapper and chill it briefly before opening.
  3. 3Lie down or use the position recommended by your care team.
  4. 4Insert the suppository gently into the vagina as directed.
  5. 5Remain lying down for a few minutes if that helps reduce leakage.
  6. 6Wash your hands after insertion.

Storage and Refill Planning

Follow the storage instructions on the pharmacy label. Keep suppositories away from heat, and ask before travelling if the label requires refrigeration.

Check the beyond-use date and plan refills before the final doses. If your timing is tied to a treatment calendar, leave enough time for the pharmacy to prepare the refill.