Medication information
OTC

Diphenhydramine (Benadryl)

OTC sedating antihistamine — allergies, sleep, motion sickness

Diphenhydramine (Benadryl) is an older sedating antihistamine. Sometimes used for allergies, sleep, motion sickness, or itching. Newer non-sedating antihistamines (cetirizine, loratadine) are usually preferred for daily allergy control.

How the pharmacy helps

We stock 25 mg and 50 mg. Talk to the pharmacist before regular nightly use for sleep — alternatives are gentler.

Access framing

Available without a prescription. Call to add to a pickup.

Access

Available without a prescription. Call to add to a pickup.

Forms and strengths

Medication entries grouped here

Strengths, dosage forms, brands, or package entries may vary. Your prescription label and pharmacist counselling are the instructions to follow.

Brand / GenericStrengthFormDINRecord
Benadryl
Diphenhydramine
25mgCapsuleActive
COMMON QUESTIONS

Questions
Diphenhydramine (Benadryl) Questions

Not recommended long-term — tolerance builds and it is associated with cognitive effects in older adults. Talk to the pharmacist.
Generally avoided under age 6 for sleep; talk to the pharmacist for allergy use in children.
Significant drowsiness — do not drive after taking.

Have questions about this medication?

Call the pharmacy or bring the medication to the counter. We can help compare labels, dosing schedules, storage needs, and questions to ask your prescriber.

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