Diclofenac Topical Pain Cream

Diclofenac, also known by the brand name Voltaren®, is a non-steroidal anti-inflammatory drug (NSAID). When compounded into a topical cream, it can be applied directly to the affected area, allowing for a higher concentration of medication at the site of pain compared to taking the drug orally.

Our compounded diclofenac creams are available in concentrations ranging from 5% to 12%. We regularly stock diclofenac 6%, 8%, and 10% in Lipoderm® base, which can often be picked up the same day.

Diclofenac Topical Cream is most commonly used for pain and inflammation in joints due to arthritis. It can also be used for other conditions involving inflammation, including:

• Osteoarthritis pain
• Tendinitis and bursitis
• Muscle strains and sprains
• Localized soft tissue inflammation

Diclofenac works by blocking cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the production of prostaglandins — chemical messengers that trigger the body's inflammatory response.

The topical cream formulation allows diclofenac to be transported across the skin, resulting in a higher concentration at the area of application compared to oral administration. This targeted delivery means effective pain relief with minimal systemic absorption.

Because diclofenac cream is applied topically, very little is absorbed into the bloodstream. This significantly reduces the risk of systemic side effects commonly associated with oral NSAIDs (such as kidney or blood pressure concerns).

Local side effects may include:

• Redness at the application site
• Itching or swelling
• Numbness, burning, or tingling

Rare systemic effects:

• Fatigue, nausea, lightheadedness, or dizziness

If you experience any side effects, contact your physician or pharmacist.

This cream is for external use only.

1. Wash your hands before applying. Consider wearing a glove.
2. Pump or scoop the prescribed amount onto the affected area.
3. Rub gently until the cream is no longer visible, then continue rubbing gently for an additional 60 seconds to aid penetration.
4. Do not apply heavy pressure, as this can increase pain.
5. Replace the cap or lid.
6. Wash hands thoroughly after applying.
7. Avoid getting the area wet for at least 1 hour after application.
8. An occlusive dressing or bandage is not required.

• Store at room temperature
• Avoid extreme hot or cold temperatures
• Keep away from bright light and excessive moisture
• If you notice discoloration or separation, contact the pharmacy
• Check the expiry date on the label