Compounded triple-combination cream for melasma (Tri-Luma alternative)
Available by prescription only. Your prescriber decides the ingredients, strength, form, quantity, and directions.
Typically 24–48 hours.
A compounded triple-combination cream containing hydroquinone 4%, fluocinolone 0.01%, and tretinoin 0.05% — the same formulation as Tri-Luma — for treating melasma and hyperpigmentation.
These notes are educational and do not replace directions from your prescriber or the label on your prescription.
This is a compounded triple-combination cream containing hydroquinone 4%, fluocinolone 0.01%, and tretinoin 0.05%. It is the compounded equivalent of Tri-Luma Cream, available when the commercially manufactured product is not.
A 2007 study found that 73% of patients using this triple combination achieved improvement of more than 75%, compared to 49% using hydroquinone alone.
Each ingredient targets melanin production through different mechanisms:
We can explain prescription details, storage, packaging, refill planning, and what to ask before the prescription is changed.
Monday to Friday, 9:00 AM - 6:00 PM. Call before coming in if timing, storage, or availability matters today.
[email protected]. Please avoid sending urgent clinical questions by email.
Review related medication questions, preparation considerations, and what to bring before calling or visiting.
For milder hyperpigmentation, single-ingredient hydroquinone cream may be sufficient.
Scar routines may also involve pigmentation, texture, and base-selection questions.
Another dermatology compound where base choice, application site, and irritation history matter.
Compounded skin-lightening cream for melasma and hyperpigmentation
Compounded topical spray for hair loss in men and women
Compounded creams for scar reduction including acne scars and keloids
This website does not provide medical advice. The information is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or qualified health care provider.
Send the prescription or call the pharmacy. We can review preparation requirements, timing, and storage questions before you come in.