Nifedipine Ointment

Nifedipine ointment is a medicated rectal ointment, commonly compounded at 0.2%, 0.3%, or 0.5% strength when prescribed. It is one smooth-muscle relaxant option used in anal fissure care plans.

Diltiazem 2% may be prescribed instead of nifedipine. These are alternative active ingredient approaches, not ingredients that are normally combined together unless the prescription specifically says so.

Anal fissures are often associated with internal anal sphincter spasm and reduced blood flow to the irritated area. Smooth-muscle relaxant ointments are prescribed to reduce sphincter tone and support the healing environment.

The prescriber chooses the active ingredient, strength, base, directions, and length of treatment. The pharmacy prepares the prescription and explains practical use.

Prescriptions may specify one of these active ingredient options:

• Nifedipine 0.2%, 0.3%, or 0.5%
• Diltiazem 2%

Optional add-ons may include lidocaine 1% or 2% for local numbing, or hydrocortisone 1% or 2% when a corticosteroid is part of the prescriber's plan. Vaseline is the default base unless the prescription requests a different base.

1. Wash hands before and after application
2. Apply the amount directed on the prescription label
3. Apply as directed to the affected rectal area
4. Many prescriptions are written for use 2–3 times daily and after each bowel movement
5. Continue for the treatment period written by the prescriber unless told otherwise

Ask the care team before changing the dose, stopping early, or combining with other rectal products.

Side effects are very uncommon and usually occur only at the start of therapy:

• Perianal itching or soreness
• Headache
• Light-headedness or flushing